Figure 4
i.p. LPS priming produces peripheral blood neutrophilia, followed by neutropenia and lung neutrophil sequestration, after MHC I mAb challenge.
(A) Peripheral neutrophils in control mice and mice administered i.p. LPS (0.1 mg/kg) with and without MHC I mAb (1.0 mg/kg). **P < 0.05 vs. other groups. (B–D) Representative Gr-1 mAb immunostaining in (B) control mouse lungs, (C) mice administered i.p. LPS (at 24 hours after injection; 0.1 mg/kg), and (D) mice administered i.p. LPS (0.1 mg/kg) and MHC I mAb (1.0 mg/kg) at 2 hours after injection. Original magnification, ×400.
