Growth hormone resurrects adult human thymus during HIV-1 infection
J. Clin. Invest. Kiki Tesselaar, et al. 118:844 doi:10.1172/JCI35112 [Go to this article.]

Figure 1
Generation of TRECs. During thymopoiesis, the genes encoding the variable and constant regions of the TCR-α chain are being rearranged. This is accompanied by the deletion of the interspersed TRD@ and the formation of an episomal DNA excision circle (TREC) which can be detected and quantified by PCR.