MicroRNA15a modulates expression of the cell-cycle regulator Cdc25A and affects hepatic cystogenesis in a rat model of polycystic kidney disease
J. Clin. Invest. 118:11 doi:10.1172/JCI34922 [Go to this article.]

Figure 5
Expression of Cdc25A in liver tissue by immunofluorescent confocal microscopy.

Levels of Cdc25A were increased in cholangiocytes lining rat and human liver cysts compared with normal cholangiocytes. Original magnification, ×100 (normal human and normal rat); ×63 (ADPKD, ARPKD, CHF, PCK rat). Asterisks indicate bile duct or cyst lumen. Data are representative of 3 independent experiments.