Figure 5
Characterization of macaque K03290, an animal with normal hematopoiesis.
(A) Marking levels of K03290 in peripheral blood, which had been stabilized for more than 2 years. (B) Southern blot analysis showed multiple bands of HOXB4-overexpressing marrow cells. Digestion with SacI, which cut the transgene twice, showed a 3.9-kb band for all the integrants. BglII and EcoRI cut the transgene once, and so each band indicates an individual integrant.
