Complex two-gene modulation of lung disease severity in children with cystic fibrosis
J. Clin. Invest. Ruslan Dorfman, et al. 118:1040
doi:10.1172/JCI33754 [Go to this article.]

Figure 1
Normalized MBL2 levels corresponding to 6 MBL2 gene diplotypes (**00, XYA0, YYA0, XXAA, XYAA, and YYAA) in CF patient and parent cohorts. (A and B) Distribution of normalized MBL2 expression values and median MBL2 expression values for each diplotype is shown for 600 parents (A) and 1,393 PI CF patients (B). (C and D) Comparison of normalized MBL2 expression values between patients and parents (C) and between 848 pediatric and 545 adult patients (D). Statistical difference was tested using the Wilcoxon rank-sum test. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.