α3β1 integrin–controlled Smad7 regulates reepithelialization during wound healing in mice
J. Clin. Invest. Louise E. Reynolds, et al. 118:965 doi:10.1172/JCI33538 [Go to this article.]

Figure 5
Elevated Smad7 promoter activity in Itga3^–/– keratinocytes. WT and Itga3^–/– keratinocytes were transfected with Smad-luciferase promoter constructs pS7.5 to test for Smad7 promoter activity (A), ARE/FAST1 to test for Smad2 promoter activity (B), and CAGA to test for Smad3/4 promoter activity (C). Graphs represent mean ± SEM luciferase activity. n = 6–12 separate samples in triplicate/treatment. *P < 0.04.