Excess adenosine in murine penile erectile tissues contributes to priapism via A2B adenosine receptor signaling
J. Clin. Invest. 118:4 doi:10.1172/JCI33467
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Figure 3
Inhibition of ADA activity in wild-type mice induces potent penile CCS relaxation.

(A and B) CCSs of wild-type mice were treated with different concentrations of adenosine in the presence or absence of DCF (5 μM; A) or with 100 μM adenosine in the presence of different concentrations of DCF (0–100 μM; B). The resulting adenosine-induced CCS relaxation was monitored by force transducer. Data are means ± SEM. *P < 0.05 versus adenosine alone; **P < 0.05 versus untreated.