Retinal vascular permeability suppression by topical application of a novel VEGFR2/Src kinase inhibitor in mice and rabbits
J. Clin. Invest. Lea Scheppke, et al. 118:2337 doi:10.1172/JCI33361 [Go to this article.]

Figure 6
Topical instillation of 1.0% TG100801 achieves posterior ocular tissue exposure to the prodrug (TG100801) and the active compound (TG100572) in mice and rabbits. Ocular tissue concentration–time profile of (A) TG100801 in mice, (B) TG100572 in mice, (C) TG100801 in rabbits, and (D) TG100572 in rabbits.