Heterotaxy and complex structural heart defects in a mutant mouse model of primary ciliary dyskinesia
J. Clin. Invest. 117:12 doi:10.1172/JCI33284 [Go to this article.]

Figure 1
Situs anomalies in Dnahc5^del593 mutants.

(A) Situs solitus with levocardia. The right lung (R) has 4 lobes, and the left lung (L) has 1. Arrow indicates direction of heart (H) apex. The stomach (S) is on the left. (B) Situs inversus totalis with dextrocardia. Note 4 left (labeled 1, 2, 3, and 4) and 1 right (R1) lung lobes, with stomach on the right. (C and D) Heterotaxy with levocardia. Note right aortic arch (RAA), 1 lung lobe on each side (R1 and L1), and stomach on the right (C). After removal of the liver, azygos continuation (arrowhead) of the interrupted inferior vena was found (D). K, kidney. Scale bar in D: 250 mm (A–D).