Impaired parasympathetic function increases susceptibility to inflammatory bowel disease in a mouse model of depression
J. Clin. Invest. Jean-Eric Ghia, et al. 118:2209 doi:10.1172/JCI32849 [
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Figure 5Influence of reserpine treatment (1 μg/d for 14 days) and VXP on acetylcholine level in colonic tissue in group without colitis and group with 5 days DSS-induced colitis. VXP or colitis alone significantly decreased the level of acetylcholine in mice without colitis (
n = 10). A greater decrease was found in the colitic group with reserpine or VXP treatment (
n = 12). *
P < 0.05,
n ≥ 8. The values are shown as means ± SEM.