Estrogen receptor β protects against acoustic trauma in mice
J. Clin. Invest. Inna Meltser, et al. 118:1563 doi:10.1172/JCI32796 [
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Figure 6DPN affects BDNF expression. (
A) BDNF protein expression in the cochlea of WT, ARKO, and ERKO mice injected with either vehicle (DMSO, open bars) or DPN (gray bars). DPN treatment increased BDNF protein in ARKO and ERKO mice. Values are means ± SEM,
n = 8 cochlea in each group. *
P < 0.05; ***
P < 0.001 by 2-way ANOVA. (
B) BDNF mRNA expression in the cochlea of WT mice with or without DPN treatment. Each bar represents mRNA expression of 10 cochlea in 1 RT-PCR experiment. DPN treatment upregulated BDNF mRNA in the cochlea.