Estrogen receptor β protects against acoustic trauma in mice
J. Clin. Invest. Inna Meltser, et al. 118:1563 doi:10.1172/JCI32796 [
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Figure 4Representative western blot showing ERβ expression (upper panel) in the cochlea of WT males and females. Two independent experiments were performed with 5 mice (10 cochlea) in each group. Male (lane 1) and female (lane 2) nuclear fractions and male (lane 3) and female (lane 4) cytosolic fractions; 1 fmol ERβ-positive control (lane 5) and 20 fmol of ERβ-positive control (lane 6). Top row: ERβ was found in nuclear, but not in cytosolic, cochlear fractions of males and females. Middle row: Nuclear loading control using TATA-box binding protein. Bottom row: Cytosolic loading control using GAPDH.