Estrogen receptor β protects against acoustic trauma in mice
J. Clin. Invest. Inna Meltser, et al. 118:1563 doi:10.1172/JCI32796 [
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Figure 1ABR threshold shifts 24 h after acoustic trauma. The same group of WT male and female mice were used for comparing the different knockout animals. No significant gender difference was observed in threshold shifts. Both female (left) and male (right) ARKO (4 females, 3 males) and BERKO (19 females, 11 males) mice showed significantly elevated threshold shifts at all frequencies compared with sex-matched WT mice (17 females, 13 males). ERKO mice (6 females, 6 males) had no differences in threshold shifts compared with WT. All data are means ± SEM. **
P < 0.01; ***
P < 0.001 by 2-way ANOVA.
