The muscle-specific ubiquitin ligase atrogin-1/MAFbx mediates statin-induced muscle toxicity
J. Clin. Invest. Jun-ichi Hanai, et al. 117:3940 doi:10.1172/JCI32741 [Go to this article.]

Figure 2
Lovastatin causes reduction in myotube diameter. C2C12 myotube morphology and mean diameter following treatment with lovastatin at various concentrations (A) or for various times (B). Control (0 μM) cultures were treated with reagent vehicle alone. Original magnification, ×100.