Sustained pharmacological inhibition of δPKC protects against hypertensive encephalopathy through prevention of blood-brain barrier breakdown in rats
J. Clin. Invest. Xin Qi, et al. 118:173 doi:10.1172/JCI32636 [Go to this article.]

Figure 6
Sustained δV1-1 treatment preserves the cellular distribution of ZO-1 and occludin in hypertensive rat brain. Fresh frozen brain sections (13 weeks of age) were stained with antibodies for occludin (A) or ZO-1 (B) (green). Endothelial cells were identified by CD31 staining (red). Nuclei were stained by Hoechst (blue). Left: typical examples of 3 independent experiments. Scale bar: 0.5 μm. Right: enlargement of the area marked by the white boxes in the merged image.