Ablation of GalNAc-4-sulfotransferase-1 enhances reproduction by altering the carbohydrate structures of luteinizing hormone in mice
J. Clin. Invest. Yiling Mi, et al. 118:1815 doi:10.1172/JCI32467 [Go to this article.]

Figure 7
Uterine weights, estrogen levels, and progesterone levels are increased in GalNAc-4-ST1^–/– mice. (A) The uteri from 10 WT and 10 GalNAc-4-ST1^–/– adult female mice were collected and weighed. Means differed by 2.3-fold; P = 0.0007. The ovaries from WT and GalNAc-4-ST1^–/– adult female mice were collected and extracts prepared by sonnication. (B) Estrogen level mean values differed by 2.5-fold; P = 0.0885. (C) Progesterone level mean values differed by 5.3-fold; P = 0.0118. The levels of estrogen and progesterone were determined by RIA.