Ablation of GalNAc-4-sulfotransferase-1 enhances reproduction by altering the carbohydrate structures of luteinizing hormone in mice
J. Clin. Invest. Yiling Mi, et al. 118:1815 doi:10.1172/JCI32467 [Go to this article.]

Figure 4
Comparison of seminal vesicles and uteri from WT and GalNAc-4-ST1^–/– mice. (A) The seminal vesicles, prostate, and bladder were dissected from WT (left) and GalNAc-4-ST1^–/– (right) male adult mice. The seminal vesicles are significantly enlarged. (B) The uterus and ovaries were dissected from WT (upper 2) and GalNAc-4-ST1^–/– (lower 2) female adult mice. The uteri are enlarged in GalNAc-4-ST1^–/– mice as compared with the WT mice. (C) Histologic sections of testis from postnatal day 26 and 28, WT and GalNAc-4-ST1^–/–. Sperm can be seen in the section from GalNAc-4-ST1^–/– mice on day 28 but not in the section from WT mice on day 28. Scale bars: 1 μm.