Glypican-1 modulates the angiogenic and metastatic potential of human and mouse cancer cells
J. Clin. Invest. Takuma Aikawa, et al. 118:89 doi:10.1172/JCI32412 [
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Figure 7Effects of GPC1 levels on phospho-MAPK in subcutaneous tumors. (
A) Immunoblotting for active ERK1/2. Lysates from 10 tumors from sham-transfected PANC-1 cells, 8 tumors from GAS6 cells, and 6 tumors from GAS7 cells were subjected to immunoblotting with anti–phospho-MAPK antibody as described in Methods. (
B) Densitometric analysis. Band intensities for active ERK1 and active ERK2 were normalized to total ERK2 (loading control). Data are means ± SEM. *
P < 0.05 compared with sham.
