Glypican-1 modulates the angiogenic and metastatic potential of human and mouse cancer cells
J. Clin. Invest. Takuma Aikawa, et al. 118:89 doi:10.1172/JCI32412 [Go to this article.]

Figure 5
Effects of GPC1 levels on CD31 immunoreactivity in subcutaneous tumors. (A) Analysis of vessel number. Morphometric analysis of vessel number was performed as described in Methods, using an anti-CD31 antibody. Data are based on immunohistochemical staining of 10 tumors from sham-transfected PANC-1 cells, 7 tumors from GAS6 cells, and 10 tumors from GAS7 cells. (B) Analysis of vessel area. Morphometric analysis on the same tumors was carried out based on the area occupied by the vessels. Data are the means ± SEM. *P < 0.05 and **P < 0.01 compared with sham.