Treatment with CD20-specific antibody prevents and reverses autoimmune diabetes in mice
J. Clin. Invest. Chang-yun Hu, et al. 117:3857 doi:10.1172/JCI32405 [
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Figure 3Depletion of B cells following initiation of a course of 4 2H7 anti-hCD20 or IgG control injections. Peripheral blood cells, after removing erythrocytes, were costained with anti-CD22 and anti-B220 and analyzed by flow cytometry. B cell (CD22
+B220
+) numbers are shown at various time points after the last injection with 2H7 (circles) or control IgG (triangles). Mean values of at least 10 observations ± SE are presented.
