Treatment with CD20-specific antibody prevents and reverses autoimmune diabetes in mice
J. Clin. Invest. Chang-yun Hu, et al. 117:3857 doi:10.1172/JCI32405 [
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Figure 2Expression of hCD20 does not affect spontaneous diabetes in NOD mice. The incidence of diabetes in transgenic hCD20 mice was compared with nontransgenic mice (
A, female mice; and
B, male mice). No differences were seen in diabetes incidence (
P = 0.47 when female incidence curves compared by log-rank test and
P = 0.84 when male incidence curves compared).