Leptin resistance contributes to obesity and hypertension in mouse models of Bardet-Biedl syndrome
J. Clin. Invest. Kamal Rahmouni, et al. 118:1458 doi:10.1172/JCI32357 [
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Figure 8Effect of a 48-hour fast, with or without leptin administration, on plasma leptin and MAP in
Bbs4–/– and
Bbs6–/– mice.
MAP during fasting (with or without leptin administration) represents the average of the last 24 hours of the fasting period. Data are mean ± SEM;
n = 8 mice per group. *
P < 0.05 compared with baseline and fasting+leptin.