Leptin resistance contributes to obesity and hypertension in mouse models of Bardet-Biedl syndrome
J. Clin. Invest. Kamal Rahmouni, et al. 118:1458 doi:10.1172/JCI32357 [
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Figure 7Change in MAP induced by intraperitoneal administration of hexamethonium (1 μg/g body weight) in
Bbs2–/–,
Bbs4–/–, and
Bbs6–/– mice and wild-type littermate controls expressed in mmHg (
A) and as the percentage change from baseline (
B).
Data are mean ± SEM;
n = 5–10 mice per group. *
P < 0.05 compared with wild-type controls.