Leptin resistance contributes to obesity and hypertension in mouse models of Bardet-Biedl syndrome
J. Clin. Invest. Kamal Rahmouni, et al. 118:1458 doi:10.1172/JCI32357 [
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Figure 6Comparison of MAP (
A) and HR (
B) between
Bbs2–/–,
Bbs4–/–, and
Bbs6–/– mice and wild-type littermate controls.
Data are mean ± SEM of MAP and HR recorded continuously for 24 hours over 7 days (
n = 5–6 mice per group). Compared with wild-type controls,
Bbs4–/– and
Bbs6–/– mice had significantly elevated MAP (
P < 0.001), but
Bbs2–/– mice did not (
P = 0.678).
