Leptin resistance contributes to obesity and hypertension in mouse models of Bardet-Biedl syndrome
J. Clin. Invest. Kamal Rahmouni, et al. 118:1458 doi:10.1172/JCI32357 [
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Figure 1Representative T1-weighted MRI demonstrating greater fat mass in
Bbs2–/–,
Bbs4–/–, and
Bbs6–/– mice than in wild-type littermate controls.
Coronal (top) and axial abdominal (bottom) sections of wild-type and BBS mice are shown. With this pulse-sequence, fat appears white and muscle and water appear gray or black. The plus signs indicate subcutaneous fat, and the asterisks indicate visceral fat.