Therapeutic suppression of translation initiation factor eIF4E expression reduces tumor growth without toxicity
J. Clin. Invest. Jeremy R. Graff, et al. 117:2638 doi:10.1172/JCI32044 [Go to this article.]

Figure 1
The eIF4E ASOs. Four eIF4E ASOs were selected for the reduction of eIF4E in cultured human and murine cells. The relative position within the human eIF4E cDNA (GenBank accession no. M15353) for 4 eIF4E-specific ASOs is depicted. The sequences for the universal non-silencing ASO control and the ASO mismatch control are included. The MOE-modified bases are underlined.