Gas1 is a modifier for holoprosencephaly and genetically interacts with sonic hedgehog
J. Clin. Invest. Maisa Seppala, et al. 117:1575 doi:10.1172/JCI32032 [Go to this article.]

Table 1
Frequency of midline-centered craniofacial deficiencies in Gas1^–/–, Gas1^–/–Shh^+/+, and Gas1^–/–Shh^+/– mice