Effects of IL-7 on memory CD8⁺ T cell homeostasis are influenced by the timing of therapy in mice
J. Clin. Invest. Som G. Nanjappa, et al. 118:1027 doi:10.1172/JCI32020 [Go to this article.]

Figure 1
IL-7 treatment during the expansion phase of the CD8 T cell response. Cohorts of LCMV-infected C57BL/6 mice were treated daily with IL-7 or vehicle control PBS between days 1 and 7 after infection. On days 8 (A and B) and 41 (C and D) after infection, CD8 T cells in the spleen specific to the indicated LCMV epitopes were quantitated by intracellular staining for IFN-γ. Each symbol represents data from the spleens of individual mice.