Adipocyte LDL receptor–related protein–1 expression modulates postprandial lipid transport and glucose homeostasis in mice
J. Clin. Invest. Susanna M. Hofmann, et al. 117:3271 doi:10.1172/JCI31929 [
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Figure 7Increased food intake under normal chow–fed conditions and reduced fat mass after food deprivation in
ad-Lrp1–/– mice.
(
A) Food intake data collected from inbred
ad-Lrp1+/+ (open squares) and
ad-Lrp1–/– (filled circles) mice (
n = 12). (
B) Changes in fat as a percentage of BW in
ad-Lrp1+/+ (white bar) and
ad-Lrp1–/– (black bar) mice on the mixed background after 24 hours of food deprivation (
n = 16–18). *
P < 0.05, **
P < 0.005 compared with the
ad-Lrp1+/+ groups.