Adipocyte LDL receptor–related protein–1 expression modulates postprandial lipid transport and glucose homeostasis in mice
J. Clin. Invest. Susanna M. Hofmann, et al. 117:3271 doi:10.1172/JCI31929 [Go to this article.]

Figure 6
Analysis of fat tissues in ad-Lrp1^+/+ and ad-Lrp1^–/– mice. (A) Gross appearance of interscapular fat in inbred ad-Lrp1^+/+ and ad-Lrp1^–/– mice. (B) Gross appearance of eWAT fat pads and BAT isolated from ad-Lrp1^+/+ and ad-Lrp1^–/– mice in a mixed background. (C) eWAT fat pad and BAT mass measurements obtained from inbred ad-Lrp1^+/+ (white bars) and ad-Lrp1^–/– (black bars) mice (n = 8). (D) Histology of eWAT (original magnification, ×200) and BAT (original magnification, ×400) from ad-Lrp1^+/+ and ad-Lrp1^–/– mice on a mixed background. Scale bar: 25 μm. (E) Histology of eWAT (original magnification, ×400) and BAT (original magnification, ×600) from ad-Lrp1^+/+ and ad-Lrp1^–/– mice in homogeneous C57BL/6 background. Scale bar: 100 μm. (F) Comparison of adipocyte cell size in ad-Lrp1^+/+ and ad-Lrp1^–/– mice as measured by pixel areas. *P < 0.05, **P < 0.005, ***P < 0.001 compared with the ad-Lrp1^+/+ group.