Adipocyte LDL receptor–related protein–1 expression modulates postprandial lipid transport and glucose homeostasis in mice
J. Clin. Invest. Susanna M. Hofmann, et al. 117:3271 doi:10.1172/JCI31929 [
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Figure 2Lipid transport to adipose tissue is impaired in
ad-Lrp1–/– mice.
(
A) Fasting plasma cholesterol and triglyceride levels were similar in
ad-Lrp1+/+ (open bars) and
ad-Lrp1–/– (black bars) mice fed basal chow diet in both inbred and mixed-strain backgrounds. (
B) Plasma triglyceride levels in
ad-Lrp1+/+ (open squares) and
ad-Lrp1–/– (filled circles) mice after an oral lipid load (inbred background). The inset shows the area under the curve (AUC) analysis of the data. *
P < 0.05;
n = 10.