Modulation of prostate cancer genetic risk by omega-3 and omega-6 fatty acids
J. Clin. Invest. Isabelle M. Berquin, et al. 117:1866 doi:10.1172/JCI31494 [Go to this article.]

Figure 1
Suppression of prostate tumor proliferation by omega-3 PUFAs in vivo. Pten^P+/+, Pten^P+/–, and Pten^P–/– mice were fed the high–omega-3, low–omega-3, and high–omega-6 diet for a period of up to 24 weeks. Mouse AP, DL, and VP lobes were weighed, and the sums were expressed as milligrams per 25 gram body weight. Five mice were used per data point in a cohort of 180 mice. Open circles represent mice on the high–omega-3 diet; shaded squares, mice on the low–omega-3 diet; filled triangles, mice on the high–omega-6 diet. Horizontal bars represent averages. SDs are shown for Pten^P–/– mice fed with the high–omega-3 and high–omega-6 diet.