Dominant-negative effect of the heterozygous C104R TACI mutation in common variable immunodeficiency (CVID)
J. Clin. Invest. Lilit Garibyan, et al. 117:1550 doi:10.1172/JCI31023 [
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Figure 9C104R mutant does not interfere with surface expression of WT hTACI. 293T cells were cotransfected with the indicated hTACI plasmids, and surface expression of Flag-tagged WT hTACI and Myc-tagged C104R hTACI was analyzed 24 hours after transfection using anti-Myc–FITC and anti-Flag–PE antibodies. Mock, untransfected.
