Dominant-negative effect of the heterozygous C104R TACI mutation in common variable immunodeficiency (CVID)
J. Clin. Invest. Lilit Garibyan, et al. 117:1550 doi:10.1172/JCI31023 [
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Figure 2Self association of mTACI monomers in transfectants. (
A and
B) 293T cells were cotransfected with the indicated plasmids. IP was performed 48 hours later, followed by SDS-PAGE and Western blotting (WB). Lysates were probed for expression of tagged TACI. Results are representative of 3 experiments. The anti-GFP mAb used, JL-8, recognizes the CFP variant of GFP.