Dominant-negative effect of the heterozygous C104R TACI mutation in common variable immunodeficiency (CVID)
J. Clin. Invest. Lilit Garibyan, et al. 117:1550 doi:10.1172/JCI31023 [Go to this article.]

Figure 1
Aligned aa sequences of human and murine TACI. Cysteine residues that make up the TNFR motif have an asterisk above them; the CRD1 and CRD2 domains are underlined. The vertical lines indicate identical residues and the dots, similar residues. The open triangle denotes the human C104R mutation found in CVID and its corresponding mutation C76R in mTACI.