Prenatal dexamethasone exposure induces changes in nonhuman primate offspring cardiometabolic and hypothalamic-pituitary-adrenal axis function
J. Clin. Invest. Annick de Vries, et al. 117:1058 doi:10.1172/JCI30982 [
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Figure 4Blood pressure is elevated in 12- to 14-month-old offspring of dexamethasone-treated pregnancies. Top: Blood pressure in 8-month-old offspring (no significant differences). Bottom: Blood pressure in 12- to 14-month-old offspring. Two-way repeated-measures ANOVA, interaction between blood pressure and offspring group, F
(3,39) = 3.65,
P < 0.03; offspring group, F
(3,39) = 8.81,
P < 0.0002; post hoc, Fisher’s least significant difference method, *
P < 0.04.