Prenatal dexamethasone exposure induces changes in nonhuman primate offspring cardiometabolic and hypothalamic-pituitary-adrenal axis function
J. Clin. Invest. Annick de Vries, et al. 117:1058 doi:10.1172/JCI30982 [Go to this article.]

Figure 3
PEPCK activity in the liver is diminished in the offspring of pregnant animals given dexamethasone, coinciding with attenuated PEPCK mRNA and altered GR mRNA expression. Top left: PEPCK activity in the liver. One-way ANOVA, P = 0.0096; Newman-Keuls multiple-comparison test, *P < 0.05 versus control. Bottom left: Relative PEPCK mRNA content in the liver. Bottom right: Relative GR mRNA content in the liver. Two-way ANOVA for PEPCK and GR mRNA, F_(3,12) = 3.96; interaction between PEPCK and GR mRNA, P = 0.036.