CEACAM6 acts as a receptor for adherent-invasive E. coli, supporting ileal mucosa colonization in Crohn disease
J. Clin. Invest. Nicolas Barnich, et al. 117:1566 doi:10.1172/JCI30504 [Go to this article.]

Figure 1
Adhesion of CD-associated AIEC strain LF82 to the brush border of ileal enterocytes. (A) Phase contrast microscopy of the adhesion of strain LF82 to the brush border of ileal enterocytes isolated from a CD patient and a control. Original magnification, ×1,000. (B) Indices of adhesion of AIEC strain LF82 to the brush border of ileal enterocytes isolated from 15 CD patients and 9 controls. The number of bacteria adherent to the brush border of 30–50 enterocytes was determined. Adhesion index was expressed as the mean number of bacteria adherent to the brush border of 1 enterocyte. Two separate experiments were performed in duplicate.