Crosstalk between Gi and Gq/Gs pathways in airway smooth muscle regulates bronchial contractility and relaxation
J. Clin. Invest. 117:5 doi:10.1172/JCI30489 [Go to this article.]
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Figure 8
Multiple roles of Gi in regulating contraction and relaxation signaling in ASM.

Increased (green arrows) or decreased (red arrows) expression or function of given parameters are indicated. Dotted lines denote pathways and critical mechanisms of action from increased Gαi; dashed lines denote pathways and critical mechanisms of action from decreased Gαi. AC, adenylyl cyclase; M3R, M3-muscarinic receptor.

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