Inherited human cPLA_2α deficiency is associated with impaired eicosanoid biosynthesis, small intestinal ulceration, and platelet dysfunction
J. Clin. Invest. David H. Adler, et al. 118:2121 doi:10.1172/JCI30473 [Go to this article.]

Figure 2
Gross and histologic pathology. (A and B) Intraoperative endoscopy shows a well-demarcated ulcer in the proximal ileum with minimal surrounding inflammation. (C) A shallow jejunal ulcer involves the mucosa and submucosa. Acute inflammatory exudate covers the ulcer base (solid arrow). Neutrophils infiltrate the submucosa (dashed arrow). There are no signs of chronicity nor evidence of viral inclusion, inflammatory bowel disease, or vasculitis. Original magnification, ×100. (D) Renal-cell carcinoma, Furman grade II. Original magnification, ×100.