Artificial lymph nodes induce potent secondary immune responses in naive and immunodeficient mice
J. Clin. Invest. Noriaki Okamoto, et al. 117:997 doi:10.1172/JCI30379 [
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Figure 8Effect of PTX and FTY720 on the distribution of NP-specific AFCs after aLN transplant into SCID mice. (
A–
C) Number of NP-specific AFCs in aLNs (
A), spleens (
B), or BM (
C) of recipient SCID mice transplanted with aLNs with or without PTX treatment. (
D) Number of NP-specific AFCs in aLNs of SCID mice that received FTY720 administration on days 0, 6, and/or 14 relative to aLN transplantation (day 0). –, without PTX treatment and without NP-OVA stimulation.
