TRAIL limits excessive host immune responses in bacterial meningitis
J. Clin. Invest. Olaf Hoffmann, et al. 117:2004 doi:10.1172/JCI30356 [Go to this article.]

Figure 1
TRAIL is released into the CSF of patients with acute meningitis. (A) In CSF samples from patients with acute bacterial meningitis, the concentration of sTRAIL is significantly higher than in patients with other noninflammatory diseases (OND). **P < 0.01, Student’s t test. (B) The increased CSF/serum ratio supports an intrathecal source of sTRAIL during meningitis. **P < 0.01, Student’s t test. (C) The concentration of TRAIL in CSF correlated significantly with the cell count. Spearman’s r = 0.717; P = 0.016.