Involvement of PLEKHM1 in osteoclastic vesicular transport and osteopetrosis in incisors absent rats and humans
J. Clin. Invest. Liesbeth Van Wesenbeeck, et al. 117:919 doi:10.1172/JCI30328 [Go to this article.]

Figure 2
Expression pattern of Plekhm1. (A) The plekhm1 gene was expressed in all tissues examined, as demonstrated by a rat cDNA multiple tissue panel. (B) Western blot results of the Plekhm1 protein (confirmed by subsequent incubation of the same blot with the anti-FLAG antibody; data not shown) demonstrated that the Plekhm1 protein was expressed in human monocytes (hOCL) and osteoblasts (hOB). Moreover, expression of Plekhm1 increased during differentiation of human monocytes into osteoclasts by treatment with RANKL.