Deficiency of Src homology 2 domain–containing inositol 5-phosphatase 1 affects platelet responses and thrombus growth
J. Clin. Invest. Sonia Séverin, et al. 117:944 doi:10.1172/JCI29967 [Go to this article.]

Figure 6
Histology and immunohistochemistry of WT and SHIP1-deficient mice injected with collagen and epinephrine. (A) Sections of lung tissue were stained with Masson trichrome. Arrows point to thrombi in the pulmonary vasculature of WT and SHIP1-deficient mice. Original magnification, ×200. (B) Platelet staining (brown) revealing extensive platelet thromboemboli in WT mice and a decrease in platelet number in thrombi formed in SHIP1-deficient platelets. Original magnification, ×200.