Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP
J. Clin. Invest. 116:12 doi:10.1172/JCI29602 [Go to this article.]

Figure 8
Spontaneous anti-insulin response.

IAAs in 12-week-old female NOD (n = 10), NOD-PI (n = 10), and NOD-IGRP (n = 13) mice. Horizontal line indicates upper limit of normal for IAAs. Dotted lines indicate mean for each group. P < 0.03, NOD versus NOD-PI; P = NS, NOD versus NOD-IGRP.