Jci_page_head_homepage_01 Jci_page_head_homepage_02
Wensheng Lin, Samantha L. Bailey, Hanson Ho, Heather P. Harding, David Ron, Stephen D. Miller, Brian Popko
Published in Volume 117, Issue 2
J Clin Invest. 2007; 117(2):448–456 doi:10.1172/JCI29571
Abstract | Full text | PDF | Supplemental material
Options: View larger image (or click on image)
Medium
Figure 1
CNS delivery of IFN-γ before EAE onset ameliorated the disease course dependent on the PERK pathway.

(A) Expression pattern of total IFN-γ in the course of EAE (n = 3). (B) Expression pattern of transgenic IFN-γ in the course of EAE (n = 3). (C) Mean clinical score (n = 25). Error bars represent SD. *P < 0.05, **P < 0.01 versus IFN-γCNS–;Perk+/+; Student’s t test.