Vitamin D receptor in chondrocytes promotes osteoclastogenesis and regulates FGF23 production in osteoblasts
J. Clin. Invest. Ritsuko Masuyama, et al. 116:3150 doi:10.1172/JCI29463 [Go to this article.]

Figure 2
Normal growth-plate development in chondrocyte-specific VDR-null mice. (A–D) Toluidine blue staining of the proximal tibiae from 15-day-old Cre^–VDR^fl/fl (A and B) and Cre⁺VDR^fl/fl mice (C and D). Scale bar: 200 μm. (E) Quantification of the length of the hypertrophic cartilage zone in the proximal tibiae. (F–H) Gene expression of Col2 and Col10 in neonatal (F), 15-day-old (G), and 8-week-old (H) femora from Cre^–VDR^fl/fl and Cre⁺VDR^fl/fl mice, assessed by qRT-PCR and calculated as a ratio to HPRT mRNA copies. *P < 0.05 versus Cre^–VDR^fl/fl.