Neuronal SH2B1 is essential for controlling energy and glucose homeostasis
J. Clin. Invest. Decheng Ren, et al. 117:397 doi:10.1172/JCI29417 [
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Figure 5Neuronal SH2B1 increases leptin sensitivity. (
A)
SH2B1Tg-437 males and WT littermates were fed an HFD at age 7 weeks, and body weight was monitored weekly. (
B) Fat content of
SH2B1Tg-437 males and WT littermates fed an HFD for 9 weeks. (
C) Plasma leptin levels in
SH2B1Tg-437 males and WT littermates fed an HFD for 10 weeks. *
P < 0.05.
