Neuronal SH2B1 is essential for controlling energy and glucose homeostasis
J. Clin. Invest. Decheng Ren, et al. 117:397
doi:10.1172/JCI29417 [Go to this article.]

Figure 3
Neuron-specific restoration of SH2B1 corrects energy imbalance in SH2B1KO mice. (A) Food intake in WT, SH2B1Tg, SH2B1KO, and SH2B1TgKO-437 mice at age 14–15 weeks. (B) O2 consumption and CO2 production in WT, SH2B1Tg, SH2B1KO, and SH2B1TgKO-437 mice at age 16–17 weeks. *P < 0.05.