Inhaled iloprost suppresses the cardinal features of asthma via inhibition of airway dendritic cell function
J. Clin. Invest. Marco Idzko, et al. 117:464 doi:10.1172/JCI28949 [
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Figure 6Iloprost-treated DCs fail to boost Th2 cytokine production in differentiated Th2 cells. Bone marrow–derived OVA-pulsed DCs were treated with Iloprost or vehicle. DCs were collected and cocultured with in vitro differentiated DO11.10 OVA-specific Th2 cells, that were previously generated in the presence of IL-4, anti–IL-12, and anti–IFN-γ. Cytokines were measured in the supernatant 4 days after setting up the culture. Data are mean ± SEM. *
P < 0.05.
